From quiescence to proliferation: Cdk oscillations drive the mammalian cell cycle
نویسندگان
چکیده
منابع مشابه
From quiescence to proliferation: Cdk oscillations drive the mammalian cell cycle
We recently proposed a detailed model describing the dynamics of the network of cyclin-dependent kinases (Cdks) driving the mammalian cell cycle (Gérard and Goldbeter, 2009). The model contains four modules, each centered around one cyclin/Cdk complex. Cyclin D/Cdk4-6 and cyclin E/Cdk2 promote progression in G1 and elicit the G1/S transition, respectively; cyclin A/Cdk2 ensures progression in S...
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ژورنال
عنوان ژورنال: Frontiers in Physiology
سال: 2012
ISSN: 1664-042X
DOI: 10.3389/fphys.2012.00413